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Writer's picture崇祺 曹

Running reduces the risk of several malignancies by 72%, according to Israeli researchers.

According to a peer-reviewed study from Tel Aviv University, the aerobic activity causes organs to steal sugar away from tumors, reducing their potential to grow and spread.

According to Tel Aviv University research, those who run or engage in other aerobic activities on a regular basis reduce their risk of developing certain cancers by 72 percent.


Aerobic exercise causes some organs to be so adept at capturing sugar in the body that tumors are deprived of glucose and often unable to grow and spread, according to a peer-reviewed study published last week.


It concentrated on metastatic cancer, which is cancer that has spread from its original site in the body. Researchers believe there are significant benefits to preventing initial tumors, but they concentrated


"Physical exercise creates a hostile environment for tumors by making it difficult for them to receive glucose," lead author Prof. Carmit Levy of Tel Aviv University's Department of Human Genetics and Biochemistry told The Times of Israel.


"In this work, we demonstrated that running and other aerobic activity protects the body from the metastatic activity and revealed the mechanism by which this occurs."


The research was divided into two parts. The first step was to crunch existing data, which provided a large amount of health data on 3,000 people over a 20-year period, in order to analyze exercise habits and cancer incidence. This found that people who reported frequent high-intensity aerobic activity had 72% fewer metastatic cancer than those who did not engage in physical activity.


The second portion of the study involves tracking mice as they exercised and then examining their internal organs before and after physical exercise, as well as after being injected with cancer. Aerobic activity was observed to reduce the number of metastatic tumors in the lymph nodes, lungs, and liver in mice.

Carmit Levy, Ph.D. (courtesy of Tel Aviv University)

Levy and her colleague Dr. Yftach Gepner discovered that during activity, these organs consume a considerable percentage of the available glucose in the body. According to her, the action "transformed the organs into effective energy-consumption machines, quite similar to the muscles." The transformation was not transient; rather, "the tissues of internal organs change and become akin to muscle tissue" following regular activity.


According to Levy, this produces an environment in which tumors that require glucose struggle to develop and survive. She proposed that this explains her finding about metastatic cancer, as well as the obvious benefits of exercise in preventing other malignancies.


"We all know that sports and physical activity are beneficial to our health," Levy remarked. "Our research, which looked at the internal organs, revealed that exercise alters the entire body, preventing cancer from spreading."


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